The fast_TIGER software calculates the TIGER site rates introduced in (http://dx.doi.org/10.1093/sysbio/syr064) for a multiple sequence alignment.
The fast_TIGER program has been tested on Mac and Linux. It successfully compiled using the clang++ as well as the g++ (version 4.2.1 and 4.7.3) compilers.
There are three recommended ways to compile the fast_TIGER programm:
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(i) Navigate to the "DAAD_project" directory and compile the program by typing the command "clang++ -o fast_TIGER main.cpp" or "g++ -o fast_TIGER main.cpp" After this, you should have a new binary called "fast_TIGER" in your directory. -
(ii) Navigate to the main source folder and type make. After this, you should have a new binary called "fast_TIGER" in your directory. -
(iii) On Mac OSX, double click on the DAAD_project.xcodeproj file. This opens XCODE (if installed). Click on "Build and debug" to compile the fast_TIGER program. The executable can then be found in the "build/Debug" folder.
The program works with phylip alignments. For an alignment called "alignment.phy", type the command "./fast_TIGER dna alignment.phy" to run the program. The program will output a file called "alignment.phy_r8s.txt" that contains the rates for each site separated by line breaks.