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Adding --maxVariantFrac and --minOppositeDepth to MethylDackel (Bwameth option) #404

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LucaZanella15 opened this issue Jun 18, 2024 · 0 comments
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enhancement New feature or request

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LucaZanella15 commented Jun 18, 2024

Description of feature

Hi all,

I think that adding the possibility to provide the --maxVariantFrac option (and its --minOppositeDepth counterpart, by default set to 0) would be of great value.

The possibility to switch on and off --keepDupes (currently by default properly being on) would also be useful to account for current EM-seq library preparation technologies that produce complex libraries that have low probability of fragments having the same start and stop positions unless they are true duplicates

@LucaZanella15 LucaZanella15 added the enhancement New feature or request label Jun 18, 2024
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