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DSL2: Options for different adapters for ssDNA and dsDNA libraries within the same run. #1091

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TCLamnidis opened this issue Oct 1, 2024 · 0 comments
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DSL2 enhancement New feature or request

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@TCLamnidis
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ssDNA libraries have a different R2 adapter than dsDNA libraries, meaning that processing both types of libraries together currently requires an adapterlist to be provided.

Omission of the list leaves behind small proportion of adapter sequences in PE sequences ssDNA libraries. The proportion of adapters is still small enough that it might be missed by the end user.

Screenshot 2024-10-01 at 14 22 19

To bring attention to this fact, and to make it easier to process both dsDNA and ssDNA libraries in one run, it would be good to add a second pair of parameters to specify forward and reverse adapter sequences for ssDNA libraries.

@TCLamnidis TCLamnidis added enhancement New feature or request DSL2 labels Oct 1, 2024
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