diff --git a/.changeset/little-meals-enter.md b/.changeset/little-meals-enter.md
new file mode 100644
index 0000000000000..4d29cef25739f
--- /dev/null
+++ b/.changeset/little-meals-enter.md
@@ -0,0 +1,5 @@
+---
+"gradio": minor
+---
+
+feat:Apply Zero GPU for `gr.ChatInterface`
diff --git a/gradio/chat_interface.py b/gradio/chat_interface.py
index 691ea88149502..b97e69f92f7ed 100644
--- a/gradio/chat_interface.py
+++ b/gradio/chat_interface.py
@@ -331,8 +331,10 @@ def _setup_example_messages(
         return examples_messages
 
     def _setup_events(self) -> None:
-        submit_fn = self._stream_fn if self.is_generator else self._submit_fn
         submit_triggers = [self.textbox.submit, self.chatbot.retry]
+        submit_fn = self._stream_fn if self.is_generator else self._submit_fn
+        if hasattr(self.fn, "zerogpu"):
+            submit_fn.__func__.zerogpu = self.fn.zerogpu  # type: ignore
 
         submit_event = (
             self.textbox.submit(