diff --git a/src/adapters/Cornerstone/Segmentation.js b/src/adapters/Cornerstone/Segmentation.js
index 9ed1ec82..32153e15 100644
--- a/src/adapters/Cornerstone/Segmentation.js
+++ b/src/adapters/Cornerstone/Segmentation.js
@@ -4,7 +4,8 @@ import Segmentation_4X from "./Segmentation_4X";
 const Segmentation = {
     generateSegmentation,
     generateToolState,
-    fillSegmentation
+    fillSegmentation,
+    generateSegmentationFromDatasets
 };
 
 export default Segmentation;
@@ -111,3 +112,30 @@ function fillSegmentation(
         `No generateSegmentation adapater for cornerstone version ${cornerstoneToolsVersion}, exiting.`
     );
 }
+
+/**
+ * generateSegmentationFromDatasets - Fills a derived segmentation dataset with cornerstoneTools `LabelMap3D` data from Dataset instead of images
+ *
+ * @param  {object[]} dataset An empty segmentation derived dataset.
+ * @param  {Object|Object[]} inputLabelmaps3D The cornerstone `Labelmap3D` object, or an array of objects.
+ * @param  {Object} userOptions Options object to override default options.
+ * @returns {Blob}           description
+ */
+function generateSegmentationFromDatasets(
+    datasets,
+    inputLabelmaps3D,
+    options = { includeSliceSpacing: true },
+    cornerstoneToolsVersion = 4
+) {
+    if (cornerstoneToolsVersion === 4) {
+        return Segmentation_4X.generateSegmentationFromDatasets(
+            datasets,
+            inputLabelmaps3D,
+            options
+        );
+    }
+
+    console.warn(
+        `No generateSegmentationFromDatasets adapater for cornerstone version ${cornerstoneToolsVersion}, exiting.`
+    );
+}
diff --git a/src/adapters/Cornerstone/Segmentation_4X.js b/src/adapters/Cornerstone/Segmentation_4X.js
index ce34e1e1..2524e209 100644
--- a/src/adapters/Cornerstone/Segmentation_4X.js
+++ b/src/adapters/Cornerstone/Segmentation_4X.js
@@ -23,7 +23,8 @@ import cloneDeep from "lodash.clonedeep";
 const Segmentation = {
     generateSegmentation,
     generateToolState,
-    fillSegmentation
+    fillSegmentation,
+    generateSegmentationFromDatasets
 };
 
 export default Segmentation;
@@ -41,6 +42,27 @@ const generateSegmentationDefaultOptions = {
     rleEncode: true
 };
 
+/**
+ * generateSegmentationFromDatasets - Generates cornerstoneTools brush data, given a stack of
+ * imageIds, images and the cornerstoneTools brushData.
+ *
+ * @param  {object[]} datasets An array of cornerstone image datasets that contain the metadata for each instance
+ *                             and a property _meta with empty array (required for compatibility with other dcmjs functions)
+ *                             The dataset for each instance of image can be generated with `cornerstone.metaData.get('instance', imageId)`
+ * @param  {Object|Object[]} inputLabelmaps3D The cornerstone `Labelmap3D` object, or an array of objects.
+ * @param  {Object} userOptions Options to pass to the segmentation derivation and `fillSegmentation`.
+ * @returns {Blob}
+ */
+function generateSegmentationFromDatasets(
+    datasets,
+    inputLabelmaps3D,
+    userOptions = {}
+) {
+    const multiframe = Normalizer.normalizeToDataset(datasets);
+    const segmentation = new SegmentationDerivation([multiframe], userOptions);
+    return fillSegmentation(segmentation, inputLabelmaps3D, userOptions);
+}
+
 /**
  * generateSegmentation - Generates cornerstoneTools brush data, given a stack of
  * imageIds, images and the cornerstoneTools brushData.
diff --git a/src/derivations/DerivedDataset.js b/src/derivations/DerivedDataset.js
index c7caa77d..991ed288 100644
--- a/src/derivations/DerivedDataset.js
+++ b/src/derivations/DerivedDataset.js
@@ -38,7 +38,7 @@ export default class DerivedDataset {
         this.referencedDataset = this.referencedDatasets[0];
         this.dataset = {
             _vrMap: this.referencedDataset._vrMap,
-            _meta: this.referencedDataset._meta
+            _meta: this.referencedDataset._meta || []
         };
 
         this.derive();