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⚡ replace picard/markduplicates with samtools/markdup #71

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3 of 7 tasks
bunop opened this issue Apr 4, 2024 · 0 comments
Open
3 of 7 tasks

⚡ replace picard/markduplicates with samtools/markdup #71

bunop opened this issue Apr 4, 2024 · 0 comments
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performance Improve the performance or better resource management

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@bunop
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bunop commented Apr 4, 2024

According to samtools/markdup documentation, there are additional steps to be done before calling the markdup steps. This steps are performed by bam_markduplicates_samtools nf-core subworkflow, however they need to be performed before the sort step (that is done during alignment)

  • install samtools/markdup module
  • patch samtools/markdup module to produce reports
  • fix and rename cram_markduplicates_picard local subworflow
  • install bam_markduplicates_samtools nf-core workflow
  • remove picard/markduplicates modules and configuration
  • check samtools/markdup with MultiQC config
  • test --save_cram option
@bunop bunop added the performance Improve the performance or better resource management label Apr 4, 2024
@bunop bunop modified the milestones: release v0.6.0, release v0.7.0 Apr 4, 2024
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Labels
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