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Detect Runs of Homozygosity and Runs of Heterozygosity in diploid genomes

R-CMD-check codecov.io CRAN version

This repository contains the source code for the R package detectRUNS and related performance tests. Here's the directory content:

├── detectRUNS
├── performance
├── README.md
└── TODO

detectRUNS implements two statistical approaches to runs' detection:

  • a sequential approach (consecutive runs, as described in Marras et al. 2015, and implemented in the software package Zanardi: https://github.com/bioinformatics-ptp/Zanardi);
  • an approach based on overlapping sliding windows (à la Plink: Purcell et al. 2007)

More info in the Google Doc (https://goo.gl/yXR7iA)