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DESCRIPTION
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DESCRIPTION
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Package: HurdleNormal
Title: 'Estimation and sampling for multi-dimensional Hurdle models on a Normal density with applications to single-cell co-expression'
Version: 0.98.8
Authors@R: person("Andrew", "McDavid", , "[email protected]", role = c("aut", "cre"))
Description: A Hurdle model is a modification of a distribution at zero. This
package provides routines to estimate and sample from multivariate Hurdle models
on a Normal density. These are distributions that are conditionally Normal,
but with singularities along the coordinate axes, so generalize a univariate zero-inflated distribution.
The main functionality is to estimate graphical models using group-lasso penalized neighborhood selection,
and has applications to modeling gene-gene interactions in single cell gene expression.
Depends:
R (>= 3.4.0)
License: GPL-3
LazyData: true
Imports:
glmnet,
stringr,
Rcpp (>= 0.12.10),
RcppArmadillo,
numDeriv,
nloptr,
ggplot2(>= 3.0.0),
reshape2,
reshape,
data.table,
Matrix,
methods,
stats,
utils,
plyr,
MASS
Suggests:
testthat,
parallel,
directlabels,
knitr,
rmarkdown,
huge,
igraph,
netbenchmark,
Mus.musculus,
MAST,
DT,
Hmisc,
GGally,
dtplyr,
Cairo,
dplyr,
purrr
LinkingTo: RcppArmadillo,
Rcpp
RoxygenNote: 7.1.2
VignetteBuilder: knitr
Encoding: UTF-8